Tommy places a bid to buy out the hospital with the intention of firing Kate as soon as the deal goes through; as Valerie continues her affair with Danny, Jack lets Danny know that he's aware of their relationship; Elizabeth is readmitted after Andy beats her again, and Andy takes his revenge when Dennis attempts to help his sister escape the cycle of spousal abuse; a mysterious biohazard accompanies a patient admitted to the E.R., and immediately begins to fell the staff; after Kate pleads the hospital's case, Jack agrees to counter Tommy's offer, but only if Phillip fires Danny; Kate and Tommy threaten to expose each other's secrets; after Diane's work for the last two years is called into question and her grant money is suspended, she decides to go to Africa to do research with a colleague; Tommy courts Aaron's support; feeling under-appreciated and ill-respected, Camille resigns; realizing that Tommy will stop at nothing to destroy her, a desperate Kate flees with their daughter an

Austin est sidérée d'apprendre que Tommy Wilmette, son ex-mari, a présenté au conseil de direction de l'hôpital une offre pour acheter "Chicago Hope". La nouvelle est d'autant plus déconcertante que la jeune femme doit bientôt être nommée responsable du service de chirurgie de la clinique. Grad apprend que la bourse destinée à la recherche qui devait lui être allouée a été suspendue à cause de la nature de ses découvertes. Austin contacte Jack Calverton, dans l'espoir de persuader sa famille de se porter acquéreur de l'hôpital.