Skin and Bones is a live acoustic album by the Foo Fighters released on November 7, 2006.

The 15-track set was recorded on August 29, 30 and 31, 2006 at the Pantages Theater in Los Angeles and spotlights an expanded eight-piece lineup featuring violinist/singer Petra Haden, former Germs/Nirvana/Foo Fighters guitarist Pat Smear, Wallflowers keyboardist Rami Jaffee, and percussionist Drew Hester. Haden and Jaffee had appeared as guest musicians on the band's previous studio album, In Your Honor.

A three-song encore consists of Grohl's solo performances of "Friend of a Friend", "Best of You", and "Everlong".

A DVD of the original shows, featuring a total of 20 songs, was released on November 28, 2006. It was directed by Danny Clinch, who appears briefly on-stage to play harmonica on the song Another Round, reprising the contribution he made to the original album recording of the song for In Your Honor.