Nonnatus House welcomes two new nuns. Valerie deals with a shocking case that arrives unexpectedly, and the other midwives must handle a complicated multiple birth.
Lucille helps elderly hoarder Clarice Millgrove who is struggling to keep her independence; Sister Hilda and the team work hard to help a Ghanaian family with an undiagnosed illness; Violet puts herself forward in the upcoming elections.
Valerie helps a struggling mother accept her son's birth defect. The Turners oversee a measles vaccination trial at the clinic as the team prepare for the Whitsun bank holiday.
Poplar welcomes a brand new cervical cancer-screening clinic to the Institute and Dr Turner, Shelagh and Trixie are pleased to be part of the exciting new venture.
Mother Mildred returns and helps a docker family tackle end-stage pneumoconiosis. Lucille cares for an unmarried teenage mother who wants to keep her baby.
Sister Hilda digs deep to give her terminally-ill patient her final wish whilst the Turners must prepare to say goodbye to May. Fred and Reggie are keeping secrets from each other.