Lori Ann Slesinski vanished in 2006, and police believed the prime suspect, her friend Rick Ennis, was the last to see her alive, and he killed his parents when he was 12.

When Gretchen Anthony's friends and family began receiving texts saying she had coronavirus, they grew worried. Then the messages stopped. Was she sending the texts, or was someone using COVID-19 to cover up her disappearance? Peter Van Sant reports.

Kidnapped at gunpoint, Schanda Handley knew exactly who was behind it -- her ex-husband, Michael Handley; a tumultuous relationship riddled with threats and assaults turned even more hostile the day Schanda was convinced she would die.

In 1987, Terry Wood comes home to find his wife, Roxanne Wood, dead; investigators preserve DNA, but technological limitations of the time turn the case cold, until now.

Detectives link the 1982 murders of two women near Breckenridge, CO, through matching orange socks, but the case goes cold for decades until investigators turn to genealogy for clues.

In 1998, police charge 14-year-old Michael Politte with the murder of his mother, Rita, after she was hit on the head and set on fire in her Missouri home; a jury sentences him to life without parole until a law passes that may give him a chance.

A night of music and hot-tubbing leads to professor Marianne Shockley's death and former psychologist Clark Heindel killing himself; police charge Shockley's boyfriend, Marcus Lillard, with her death.

Joseph Elledge reports his wife Mengqi Ji missing; they uncover her remains buried under a juniper tree; police try to use DNA found on that tree to catch her killer.

Olympic equestrian-turned-trainer Michael Barisone claims temporary insanity when police charge him with the attempted murder of Lauren Kanarek, a student he shot twice in the chest after she tried to ruin his reputation online.

Millionaire mother Pam Hargan, and her adult daughter, Helen, are found murdered in their northern Virginia home. Police tell the family that it looks like a murder-suicide. Did Helen shoot her mom and then take her own life, or is something else at play?

Melissa Turner of Florida called 911, saying she had discovered her fiancé, Matthew Trussler, lying unresponsive near their swimming pool; he was pronounced dead at the scene in October 2019, but an autopsy later revealed he died from stab wounds.

Peter Van Sant examines the final chapter in the case against Jacob Nolan, who claims his cousin and psychiatrist, Dr. Pamela Buchbinder, brainwashed him into attempting to kill her ex-over, Dr. Michael Weiss, while in a custody battle for their son.

In 1997, four families from Texas and Oklahoma are crushed when their daughters go missing, and the cases go cold; decades later, the serial killer himself helps investigators solve those murders.

Criminology Ph.D. student Bryan Kohberger is charged with the murder of four University of Idaho students.

Three masked gunmen broke into bank manager Michelle Renee's California home in November 2000 and forced her to rob her own bank to save her daughter Breea's life. Then, her abductor falsely claimed Michelle was in on the crime.

Alisa Mathewson suffered a 55-hour ordeal that almost cost her life at the hands of her estranged husband, Trevor Summers; she shares her harrowing experience of being kidnapped and sexually assaulted, with Peter Van Sant.

Three days after Kassanndra Cantrell's 2020 disappearance, police discover eerie surveillance footage of her attacker and soon realize the two were linked by a secret.

Angelina Fernandes, then 11-years-old, witnessed her mother, Stephanie, in distress at a bloody crime scene. She claimed she acted in self-defense when she fatally stabbed her fiancé Andy Wagner. But it would be up to a jury to decide what happened.

Donna Ongsiako was alone in her New Jersey home when she heard a noise downstairs; she thought she forgot to let the cat in, so she opened the door; there, she suffered a horrific knife attack by an unusual suspect; Jim Axelrod reports.

Tiffiney Crawford, a wife and mother, was found dead in her van with two bullet wounds to her head and a gun in her hand. Investigators' first impression was that it was a suicide, but they soon realised it might be a murder. David Begnaud reports.

On Feb. 19, 1982, Jim Krauseneck tells police he found his wife Cathy dead in their bed with an axe in her head. For four decades, Cathy's murder remained unsolved, and it was dubbed one of the oldest and coldest murder cases in America -- until now.

In May 2023, an Idaho jury finds Lori Vallow Daybell guilty of murdering her two children, JJ Vallow and Tylee Ryan, and conspiring in the murder of her husband Chad Daybell's ex-wife, Tammy; Jonathan Vigliotti reports.

Diana Duve was last seen alive leaving a bar in Vero Beach, Florida, with her on-again, off-again boyfriend, Mike Jones. Her mother knew something was wrong when Diana didn't call her, something she did every day. Does Jones know more than he claims?

A night out for two friends in Los Angeles ends in tragedy after masked men dropped them off at separate hospitals. The young women died from drug overdoses, and police immediately suspected foul play. Jonathan Vigliotti investigates.

Criminology Ph.D. student Bryan Kohberger is charged with the murder of four University of Idaho students. Kaylee Goncalves, Ethan Chapin, Xana Kernodle and Madison Mogen were found dead in their off-campus home in Nov. 2022. Peter Van Sant reports.

In August 2022, after 46 years, the last of three men convicted of kidnapping 26 children and their bus driver was paroled from a prison in California; survivors of that harrowing event share powerful and emotional interviews with David Begnaud.

A beauty stylist is almost murdered in 2016 by a client who comes to her home and poisons her with a piece of cheesecake; the motive doesn't make sense to police until they realize that the stylist and the client have an uncanny physical resemblance.