David Letterman passes Sarah Silverman the Stupid Pet Tricks torch and shares with her a very special Top Ten List. Also, Sarah meets the SPT staff and smooths out some unexpected intra-office issues. On stage, Sarah welcomes a former rodeo clown and his shockingly agile best friend, a goat who can walk on two legs, a party animal that really knows how to get down, and a dog that's up there with the smartest animals in the world. But only one will take home the title of Stupidest Pet Trick of the Week!

Sarah tries to take the high road as Jack McBrayer drops in on the SPT Writers Room to brag about his new famous piece of clothing. Also, Sarah welcomes a world record-seeking dog, an overexcited horse, and a juggling duck.

After learning that the show is over-budget, Sarah is forced to make some layoffs and Judd Apatow fights for his job. Meanwhile, Sarah hangs out with a ninja warrior hamster, a chill chameleon, a rabbit athlete, and a skateboarding bulldog.

Emmy-Winning actor Jon Hamm drops in with his pet turtle to show Sarah their impressive culinary skills. Shenanigans ensue at the SPT offices, when one of the writers goes off-the-rails with their gluten free diet, driving everyone to the point of no return. On stage, Sarah is introduced to a dog who could play for the Harlem Globetrotters, a pig who is incredibly good at sitting, staying, and rolling over, and an animal from down under who can pack a punch! But, as always... only one will take home the title of Stupidest Pet Trick of the Week!

Sarah confronts rival animal show host Jack McBrayer who is trying to poach the Stupid Pet Tricks wardrobe stylist. Also, Sarah meets goat twins and their twin owners, an acrobat and her trained fancy rats and a cowboy bulldog.

Musician Reggie Watts stops by with his pet fish to share a few movie reviews. Also, a spider who can understand Yiddish, a painting pig, and a dog and his owner who can parkour and flood the set with oos and awws.

Comedian and roast master Jeff Ross brings no mercy to the stage as he (verbally) annihilates all animals in his path in a speed roast you don't want to miss. Over on stage, Sarah watches a high jumping fox break their own record, an orange tabby who hates lasagna but loves to solve puzzles, a rescue pup who refuses to let their owner go on holiday without them, and a UFO hunter who's sexy parrot knows how to work a room... and a pole. Only one can be crowned Stupidest Pet Trick of the Week!

Backstage, Comedian and TV Personality Howie Mandel surprises Sarah with a secret, while Sarah surprises Howie with one of her own. Then, Sarah takes the time to share a cause close to her heart and receives a phone call from a big-time Hollywood director. Also, Sarah meets a ripped gym owner and her pint-sized Boston terrier that can read, a dog that can do magic tricks, a hand-model with a bell-ringing rabbit, and a daredevil kitten. However, only one of them will own the title of Stupidest Pet Trick of the Week!

David Letterman takes Sarah on an expensive stroll down memory lane. Then, back on stage, Sarah welcomes a brilliant roller-skating parrot, an acrobatic dog, a cat who can drive a car, and a bunch of racing roaches.