Dr. DU showed his remarkable talent for medicine but experienced the uncertainty of life in a disaster twenty years ago. After losing his beloved girlfriend and mentor in the same accident, Dr. DU left the disappointed healthcare system and became an EMT in a small clinic. However, he never gives up any life and makes up for his guilt in every service.With his frenemy Dr. LEE and associate Fr. HSU all around his life in critical moments, he has to deal with patient-provider relationships and life value differences between colleagues. Dr. DU believes that the only way to reform the medical system is to be part of it again. However, the mysteries about the disaster twenty years ago will blow his life in more time.

集天賦與實力於一身的醫生杜樂生，在20年前一場巨大災難中，親身經歷了生命無常、體制無情！他離開令他失望的醫院體制，從此隱身在小診所中，用自己的方式搶救緊急患者，爭分奪秒不願放棄一線生機。然而，接連不同的醫療事件發生，讓杜樂生了解到他必須改革體制，但這個決定也將引爆20年前大災難真相所隱藏秘密⋯⋯。

集天赋及实力于一身的医生杜乐生，在20年前一场巨大灾难中，亲身经历生命无常、体制无情！在这场意外中，他失去挚爱的女友与情同家人的精神导师，之后他离开令他失望的医院体制，隐身在小诊所中用自己的方式，化身医疗外送员，抢救紧急患者，争分夺秒不愿放弃一线生机。也透过一次次出动、抢救生命的过程，修补自己内心的创伤与愧疚。同时，杜乐生与地方综合医院的副院长李志豪间亦敌亦友的强强对决，加上处事强悍但内心柔软的女医生徐敏安总在关键时刻介入；接连不同的医疗事件发生，所面临种种医病之间的人情、同僚之间的价值观及自我的感情认同，让杜乐生了解他必须重回体制，才能真正改革体制，但这一决定却也成了20年前大灾难真相所隐藏的秘密引爆点……

滿腔熱血的院長率領一群認真負責的醫療團隊，在經營不善的地方醫院大刀闊斧改革，企圖扭轉它的命運。