A young aspiring artist suddenly comes down with flu-like symptoms and a swollen face. To make matters worse, his eyes are yellow, he has trouble breathing, and one of his eyes protrude strangely. It turns out that he has Lemierre's syndrome. An active girl's life is put on hold when she starts feeling fatigue and out of breath. Later, she also starts experiencing extreme joint pain, and she gets diagnosed with Lyme's disease. However, further testing shows that the girl has Babesiosis, in addition to chronic Lyme's disease. An active middle-aged woman becomes concerned when she suddenly feels lumps in her chest. After getting them removed, she then starts experiencing bleeding from her right breast. After getting that taken care of, though, she feels a growing lump in her right breast, which turns out to be two surgical sponges.

Dr. Jeffrey Roberts und seine Kollegen bekommen es am Arrowhead Regional Center in Colton, Kalifornien, mit einer seltenen Infektionskrankheit zu tun. Ein Patient wird mit schweren Körperfunktionsstörungen in die Notaufnahme eingeliefert: Seine Augen sind gelb gefärbt, was auf eine Beeinträchtigung der Leber hinweist, außerdem klagt der 21-jährige Grafikstudent über Atemprobleme. Patrick Abraham leidet unter dem sogenannten Lemierre-Syndrom. Sein Körper kämpft gegen gefährliche Bakterien an.