The Six O'Clock Show was a regional television magazine show broadcast in the Greater London area and produced by London Weekend Television between 1982 and 1988.

The Friday evening programme was launched on Friday 8 January 1982 and presented in front of a live studio audience by Michael Aspel with co-hosts Danny Baker, Andy Price and Janet Street-Porter. Later presenters included Paula Yates, Shyama Perera, former Page 3 model Samantha Fox and Mastermind champion Fred Housego.

Devised by Greg Dyke and intended as a light-hearted introduction to the weekend, the programme included a 15 minute news bulletin produced by Thames Television alongside current affairs, features and entertainment. There was also a short-lived Saturday edition of the programme, which ran for six weeks during May and June 1985. The Six O'Clock Show went onto become one of the most watched regional TV programmes in Britain.

Concern from the Independent Broadcasting Authority about the lack of a proper local news service at weekends forced LWT to introduce its own service of LWT News bulletins throughout the weekend in 1988. The Six O'Clock Show was axed around the same time and replaced by a smaller scale magazine show entitled Friday Now. This in turn was replaced a year later by Six O'Clock Live, presented by Frank Bough with reporters Danny Baker, Jo Sheldon and Nick Owen.