Kosaku is placed in isolation again, in order to receive treatment to raise his white blood cell count. Kinpachi worries about him, but Kosaku urges him to turn his attention toward his students who are preparing for high school entrance exams.

再び無菌室に入った幸作（佐野泰臣）を心配する金八（武田鉄矢）だが推薦入試を控えた３Bを気遣うよう幸作に助言される。一方、美紀（森田このみ）の父親が自殺を図り…。