Noxee Maqashalala was a South African actress best known for her role as Viwe in the first three seasons of the SABC1 youth drama series Tsha Tsha, from 2003 to 2005.

She starred as Mandisa in the SABC1 drama series Intersexions, in 2010. In 2014 she replaced Charmaine Mtinta in the role of Pearl for the second and third seasons of the SABC2 sitcom Gauteng Maboneng. In 2016 she starred in the e.tv drama series The Kingdom - uKhakhayi, where she played Nopasika, the haughty wife of a ruthless and cunning paramount chief. The following year she starred in the e.tv drama series Easy Money as Zee, a supermarket cashier and the eldest of three daughters who is desperate for her mother's approval.

In 2018 she had the lead role on the SABC1 drama series Diamond City, where she played Zandile, a prolific public protector who finds herself behind bars in Diamond City after she gets arrested for murder. The series later streamed on Netflix.

Other television series she appeared in include SABC1 soapie Generations, the SABC2 comedy Dream World, the kykNET soapie Binnelanders, the international series Tarzan: The Epic Adventures and e.tv soapie Rhythm City.

Noxolo died in her home in Honeydew, Johannesburg of causes unknown in March, 2021.