While their daughter is taken in by a religious commune led by the mysterious Reverend Brother, the Copelands meet a man with the cure to the plague.

A horde of vicious feverheads and flesh-eating parasites force the Copeland's into a plague isolation unit.

After accepting help from an old friend, a deathly omen torments Karen; the Copelands learn that no refuge is truly safe.

When the family splits up, Josh leads half the party to a nearby university to find a prophetic professor, while Karen leads the others to a nearby summer camp on a supply mission.