Hornstock is a murder suspect when his third ex-wife is killed, so he turns to Rosewood and Villa to help him clear his name.

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When pathology students work with the team on a cold case, their findings impact the entire Rosewood family.

When a victim, presumed dead, wakes up on Rosie's autopsy table, the team is thrown into a world in which people go to great lengths to keep their secrets hidden. Both Rosie and Villa are forced to re-examine the meaning of family, and Rosie's search for a Magic City Lab investor leads him to a surprising candidate.

Rosewood and Villa head back to Villa’s roots in Little Havana to investigate a vigilante who may be guilty of murder. Villa learns that her brother, Marcos, has a surprising connection to the case, and Rosie receives news of a complication regarding his kidney transplant