The Conner family is thrown back together in a haze of blood and confusion, as prodigal son Griffin returns to his second family home - Bethune General Hospital.

Brian resolves to improve his patient interaction after receiving several complaints, while Griffin forms an unlikely bond with a cantankerous war veteran. Dr. Tuttle refuses to consider Sandy’s diagnosis of a rare disease in a dancer.

When Rebecca is brought into the ER with a mysterious paralysis creeping up her body, Allen has to scramble to find out what's happening before it's too late.

A tumultuous day at the hospital gives way to an awkward dinner with Brian’s family, leading to an astonishing revelation for Sandy.

An explosion rips through the downstairs of Beth-H, changing lives there forever.

Exhilarated by her new romance with Cutler, Mel is uncharacteristically reckless in the operating room.

A clumsy attempt at addressing Griffin’s drug problem pushes him further down the spiral.

Mel does everything in her power to save a gravely wounded Sandy, while Griffin finally confronts the reality of his addiction.