The body of a young Romanian abandoned in the suburbs is found by Walter Battiston. The first suspect in the murder is an operator of the family home where the young man was a guest. Alessia Moretto zealously leads the investigation and, believing she has discovered the truth, she arrests an operator of the foster home.

Investigations into a road accident involving a mother and her child lead the police to investigate the Torrione area. Donna Rosalba, to avoid excessive police attention on the territory controlled by the crime family, turns over an alleged pirate to the investigators.

The lifeless body of a boy with a syringe still stuck in his arm leads the men of the S. Andrea police station to investigate an exclusive golf club where it seems that the boy had been involved in a clandestine relationship.

An inmate, Maria Coppola, seems to want to collaborate with the police who instruct her to find out if her cellmate, Teresa Pintauro, is actually responsible for a crime of which she accused herself, thus arousing more than one suspicion. In reality Coppola will demonstrate that he has completely different intentions.

A delegation of illegal parkers asks the policemen of the S. Andrea police station to be protected by the Pintauro clan which demands payment of the protection money from them. This is yet another sign of how Donna Rosalba's arrogance grows hand in hand with the power of the clan.

The investigations focus on a serial killer who chooses his victims among young disabled women: a blind young woman was killed and the social worker who assisted her was attacked. Suspicions focus on a convict who has already served a sentence for the rape and attempted murder of a disabled girl.

After a furious argument with Edoardo Valle, Luciano Russo disappears and his friend Genny is found dead. Some men of the police station believe that it was Luciano Russo who killed the boy, while others fear that he may have been the victim of an ambush planned by Donna Rosalba to avenge the death of her daughter Rita.

Deputy commissioner Cafasso's team manages to dismantle, after careful investigations, a highly organized gang of car thieves linked to the Neapolitan Camorra but with important ramifications abroad. The contribution of Commissioner Giorgio Pettenella, who has returned to service at the police station, is decisive.

A woman is killed and abandoned on the beach, the investigations focus on drug addicts with whom the woman had daily contact, working as a psychologist at the "Palomar" centre. The Police do not intend to leave out any investigative lead.

A well-known pop music singer found in possession of a dangerous synthetic drug agrees to collaborate with the police to arrest a drug dealer affiliated with the Pintauro gang. After the arrest of the father and the fugitive of the mother, the clan will be led by the young Pintauro, who has just returned from America.

Rosalba Pintauro and her son Tiziano seem to have disappeared without leaving any trace. An investigation that is particularly complex and delicate for the agents of the S. Andrea police station, also called to investigate the murder of a woman strangled in the bathroom of her home.

While investigating a robbery at a supermarket, the men of the police station come across a criminal game in which players-hunters chase a fleeing prey. It is feared that Alfio's father, suffering from Alzheimer's and missing for a few days, may be in the role of the prey.

The return of Sergio Amato accompanied by Stefano De Pretis is greeted with enthusiasm, while Pettenella listens attentively to some CDs that could hide the secrets of the Pintauro family. Alfio Donati is increasingly worried about his father's disappearance.

The discovery of a vast prostitution ring of girls from Eastern Europe suggests to Pettenella the idea that Silvia could work as an infiltrator together with Battiston, who will pretend to be a corrupt policeman. Meanwhile, a man is seriously injured by gunshots and, shortly after, the body of a second victim is discovered, killed by the same type of weapon.

The fight against trafficking in prostitutes is at a crucial, increasingly risky point: Silvia Esposito in the guise of Tiziana Blasi, the maitresse in contact with the prostitution ring, is "picked up" without warning by Carmine Torretta to accompany him to Ukraine to choose new girls to start off for exploitation.

Silvia's dangerous mission, infiltrated into a clan dedicated to the exploitation of prostitution, takes her to Ukraine. The already very difficult situation is further complicated when she is mistakenly arrested by the local police. Meanwhile, the elderly lady Adele is targeted by some roommates of her building.

Silvia's sacrifice to frame Carmine Torretta seems to have been in vain since the racketeer managed to escape. The inspector's frustration, transformed into anger, spills over on the woman from Torretta. For this reason, Silvia risks being excluded from the investigation.

The suicide of a wealthy lady, who had just undergone cosmetic surgery in a private clinic, offers Pietro Guerra the motivation to try to reconstruct the last days of the woman's life, also evaluating alternative hypotheses to suicide.

Luciano and Stefano investigate the murder of a barber in his shop. It will soon be discovered that the victim had made several enemies by carrying out a series of side activities such as multilevel selling and usury loans.

A bank manager's peaceful breakfast turns into a nightmare when three bandits break into his house, taking his wife and daughter hostage and forcing the man to go to the office with one of them to forcefully withdraw money.

A fire breaks out at a wine shop and the charred body of the manager is found in the rubble. The testimony of a passer-by leads the men of S. Andrea on the trail of a suspect. Claudia DiMaggio, who is under police protection, may be able to identify him, but she refuses to speak to Pietro Guerra.

The lifeless body of an antique dealer is found in an elegant apartment, all suggesting a robbery that ended in murder. Barbara saves two little boys from being attacked by a group of thugs but the two escape after stealing money from her purse.

Investigations into a dangerous arms dealer are proceeding slowly, a warehouse keeper seems to be the only link that could lead to incriminating those responsible. Following the latter's death, disguised as a suicide, the investigations go back to the high seas.

A psychotherapist is killed while talking on the phone with the deputy commissioner Cafasso who thus finds himself witnessing the crime from afar. Immediately the police direct their investigations on a psychopath, a patient of the study where the victim practiced her profession.

Claudia Di Maggio's betrayal threw Giorgio Pettenella into the deepest frustration. One thing is now clear: Claudia's collaboration with the police was determined by the desire to destroy the organization on someone's behalf.

The investigations of the S. Andrea police station are aimed at revealing the identity of the body of a man found in an escarpment, whose death dates back to about 15 years earlier. We follow the lead indicated by a woman who reveals to the investigators that 15 years earlier she was supposed to meet with her lover near the place where the body was found and that the man had never shown up for the appointment.

The agents of the Sant'Andrea police station, distraught with anger and pain for the loss of Sergio, must concentrate all their efforts to bring the killers and masterminds to justice. The investigations start from the last case followed by their missing colleague, who was investigating an organization dedicated to clandestine betting.

A cohabiting couple is found dead in the furniture showroom they ran together. The case is entrusted to the new superintendent Salvatore Sciacca who gains the trust of his new colleagues every day. The investigation initially focuses on the family of the woman killed but thanks to his intuition Sciacca will be able to correctly reconstruct a fragmentary mosaic of clues.

The body of a young woman is found at the bottom of an escarpment while Sciacca and Battiston deal with the mysterious kidnapping of a baby who had been entrusted to the babysitter. The little one could be in serious danger because he has respiratory problems. However, the agents are suspicious of a substantial withdrawal of money made by the father on the day of the child's birth.

In a small restaurant by the sea, the lifeless bodies of two Camorristi are found. The owner of the restaurant, seriously injured, is rushed to the hospital. Initially everything suggests a settlement of accounts between rival clans of the Camorra, but the case will prove to be more complex than expected.

A girl looking for help stops a car from the Sant'Andrea police station, the young woman declares that her current boyfriend has set out to find her ex, expressing his intention to kill him. The intervention of the two agents seems to restore calm, but the situation soon worsens unexpectedly.

The body of a university student is found in an attic used as an improvised neighborhood TV. At the crime scene, smashed equipment and a bloodstained easel were also found. The boy ran the small broadcaster together with his girlfriend and a friend, the three young men with their investigations had denounced the illegal activities of a Camorra boss.

The lifeless body of a girl employed as a telephone operator in a call center is found on a deserted beach. Not far away is a car parked which turns out to be registered to a man whose traces have been lost, manager of a telephone company. Suspicions focus on the victim's boyfriend who, after being questioned, attempts suicide.

A man on a scooter is hit by a runaway car. The agents of the Sant'Andrea police station intervene promptly to help him, but they do not find any type of document that can trace his identity. In the seat of the moped, which turns out to be stolen, a clue is found: a rather rare pistol.

At the Vesuvian Observatory a man convinced of having to leave his home against his will has climbed onto the roof and threatens an extreme protest: to throw himself into the void taking his child with him. Police officers will do anything to try to avert the worst.

During the demolition of an illegal building, a well-hidden entrance to a bunker is discovered. The superintendent Salvatore Sciacca arrives on the spot who, from some details, intuits that the dangerous mafioso responsible for an attack that took place some time ago in Palermo, right at the police station where Sciacca served, is hiding in the bunker.

Following the arrest of the Mafia boss Paternò, responsible for the attack on the police station where Sciacca worked in Palermo, the Sant'Andrea agents work tenaciously to uncover the links between the Mafia and the Camorra. Meanwhile in Palermo, a repentant belonging to the Paternò clan claims that Sciacca is actually a corrupt policeman, who was in turn involved in the massacre.

At the conclusion of the investigations conducted in Palermo, the chief commissioner Giorgio Pettenella completely clears the superintendent Salvatore Sciacca of being accused of being a corrupt policeman in the service of the mafia. The police continue the investigation to reveal the links of the Palermo mafia clan of the Paternò with the Neapolitan Camorra.

The body of a boy is found in the room run by a small Camorra boss, already known to the police for his cocaine trafficking. The deputy commissioner Cafasso is a longtime friend of the father of the dead boy, for this reason he will be entrusted with the thankless task of communicating the terrible news to the family.

Due to a fortuitous accident in a cemetery, it is discovered that a woman's coffin actually holds the body of another person. The mystery thickens when the autopsy reveals that the woman found in the coffin was poisoned, setting up the hypothesis of a murder never discovered before.

The body of a girl, with her head smashed, is found at the edge of a swimming pool. The victim's brother, a former water polo champion, revealed to the investigators that her sister was part of a musical group with which she used to stay until late in the evening. The police's first suspicions focus on the victim's brother and secret lover.

The agents of the Sant'Andrea police station investigate the disappearance of Dr. Veneziani, collaborator of the coroner. For some time, the woman had been on the trail of a small beggar of Albanian origin whom she had met on the street. Precisely the exploiters of the child are strongly suspected of having attacked her and reduced her to the point of death.

The body of a young psychologist is found in his office inside a family home. To give the alarm to the men of the Sant'Andrea police station was a neighborhood priest, an old acquaintance of the agents. The investigations focus on the guests of the family home and it turns out that a large sum of money has disappeared from the community coffers.

At night a group of thugs armed with iron bars enters a technical institute, devastating it. Arriving near the school, the officers find a seriously injured janitor and, half hidden by a shelf, the body of a boy. Next to the corpse an iron bar stained with blood. The police interrogate the students to reconstruct the victim's profile.

The Sant'Andrea police station is involved in investigating a massive trafficking of chemical waste which appears to have large-scale connections. Battiston is sent to prison to extort confidences from an alleged driver who may have important connections with the criminal network.

Inspector Walter Battiston, who has infiltrated the prison, tries to extract information on the shady trafficking linked to the disposal of toxic waste and to find the link that links the trafficking from northern to southern Italy. When the prisoner starts talking and confesses to Battiston that he is very worried about his brother, a small window opens to shed light on the case.

The agents of the Sant'Andrea police station investigate a crime that took place at the Platano Hotel, a small hotel for couples seeking discretion. The investigations are directed towards a shady individual living with a stripper, the victim's secret love.

Agent Luciano Russo and Superintendent Salvatore Sciacca are urgently called to the hospital where the lifeless body of a man lying on the ground was found, with his skull smashed. They will discover that the victim, admitted to the oncology department, is a shoemaker with a past as a killer.