It's a triple whammy for Roo when she gets into a compromising situation with Zach post yet another break up with EJ, finds out that Charlie has a girlfriend and learns her past big love, Andrew, is dying.
When Andrew teeters on the brink of death, Roo thinks she knows how to help but things don't go to plan, and just as Roo is feeling more confused and alone than ever, she finds support where she least expects.
In an effort to end Roo's serial dying situation, Charlie seeks advice. But will it be enough to save Zach from his dangerous 'bucket list' antics and allow Charlie and Roo to finally be together?
Roo thinks she's found the answer to all her problems when she is introduced to Marcus, a man who is her opposite - everyone he has sex with is healed.
When Roo decides the only way forward is for her to have sex with Marcus, EJ is less than on board. What if instead of Marcus healing Roo, Roo ends up killing Marcus?
In her quest to get Marcus to heal her, Roo resorts to extreme and unconventional means involving banana icecream and chicken soup. She enlists the help of EJ, but her attempts are ultimately thwarted.
Roo signs up for sexual bootcamp and misses a surprise visit from Marcus. Learning of his visit, Roo races to him but bad news about Charlie waylays her.
When Marcus seeks Roo's help, she sees a chance to use this to her advantage. She chooses Marcus over Charlie in an attempt to end her curse, but will her decision pay off?
With so much going on, Roo and EJ have a confession session that leads to some startling revelations regarding Marcus, EJ's tryst and the bile-inducing secret EJ has been guarding involving Jan.