The death of Marilyn Sheppard in 1954 is one of the most famous unsolved murders in America. The indictment of her husband, Dr. Sam Sheppard, quickly became the "Trial of the Century," then the "Re-Trial of the Century," making a celebrity out of lawyer F. Lee Bailey. Although most of the forensic evidence gathered in 1954 was ignored during Sheppard's trial, it is being re-examined with today's advanced technology. Like an intricate puzzle, the clues come together to overturn previous assumptions about the killer and point to an entirely new suspect. NOVA assembles a notable team of experts—including Barry Scheck, a well-known lawyer from the O.J. Simpson trial—and builds a precise replica of the Sheppard house, complete with the original furniture. With this unique revisiting of a vanished crime scene, NOVA investigates a horrifying and sensational milestone in forensic science.