Bester returns to Babylon 5 to shut down an underground organization that smuggles rogue telepaths out of the PSI Corps' reach. Meanwhile, Sheridan has some disagreements with Earth Force over the rent of his quarters.

A 100% fatal and 100% contagious plague is killing the Markabs. Dr. Franklin tries to find a cure, but is being opposed by the Markabs themselves, who believe the plague only affects the immoral.

Draal reveals himself to Sheridan, while Refa and Londo set a plan in motion that will lead to the final defeat of the Narns.

The new Vorlon ambassador arrives, Sheridan decides it's time to test just how effective telepaths are against the Shadow ships, and Franklin is on walkabout in Downbelow and falls in love with a singer.

In the hours before the Shadows and the Vorlons meet Sheridan's alliance at Corriana 6, Ivanova and Lorien search the last of the First Ones, and Londo races back to Centauri Prime in hope of removing all Shadow influence before the Vorlon planetkiller arrives.

Marcus and Franklin meet their liaison to the Mars resistance, but are greeted at gunpoint by the resistance itself. Meanwhile, Sheridan confronts Garibaldi about his attitude.

Four rangers come from Minbar with a status report to Delenn, while a Downbelow racketeer decides it's time to get rid of Zack.