When $60 million worth of stolen diamonds destined for a relief charity end up in the hands of casino owner Jack Catlin, MacGyver must head to the Virgin Islands to try and get them back. With the help of Chris Rhodes, a senator's daughter, MacGyver masterminds a plan to break into Catlin's vault and steal them back.

A man wants to testify against his mobster brother in Federal Court, and MacGyver has the job of keeping him safe, but the man's mother is dying and he wants to visit her.

MacGyver is trapped in a mansion with Pete, a code expert, and a government agent who may or may not be on their side. However, an old nemesis has electronically booby-trapped the entire mansion to make sure they can't go anywhere.

A mysterious person who calls himself "Viking" has just bombed the cruise ship Victoria, underway in the North Pacific Ocean. He demands six million dollars or another bomb will go off within hours. So MacGyver gets called in, along with his old Vietnam bomb-defusal partner, Charlie Robinson, to disarm it. But when they get there, they find out there's more than one bomb on the ship. Complications arise when MacGyver's partner sets off one of the bombs, and the bomber decides that DXS operated in bad faith and refuses to hand over the bomb-disarming instructions after he gets the extortion money.

After a daring escape from East Germany where he gets rescued, and in the process saves a fellow operative with a quick mechanical fix, MacGyver thinks that he deserves some peaceful vacation time. But Pete lures him into baby-sitting a Russian defector who can identify KGB agents.

In Afghanistan, wounded and hunted by the Soviets, MacGyver is given refuge by an Afghan woman and her son. But they are themselves at the mercy of an Afghan thug, who will kill MacGyver if he finds him at his woman.

At the beginning of the episode, MacGyver literally has to jump onto a moving train that he missed earlier to return top-secret files and documents to the U.S. Government. Soon after, a local tribe stops the train. They take all passengers hostage until the men responsible for the death of the tribal leader's son is found among the passengers.

Pete Thornton investigates the supposed death of an old friend, a prominent Russian dissident, and finds he must get his friend's daughter Maria out of the country before the secret police arrest her for an alleged conspiracy. However, while in Russia, Pete bumps into MacGyver, who followed him from the United States. While disappointed MacGyver followed him, Pete gladly welcomes MacGyver into his plans when the secret police arrive to take Maria into custody. Following a high speed boat chase to escape the police, Pete and MacGyver find out from Maria that her father is not dead, he is being held in a maximum security ward at a state mental institution. To get into the mental hospital, MacGyver plays the part of a mad patient and Pete plays the part of a doctor who has been assigned to him. With the help of the other patients, MacGyver is able to escape into Ward Zero, where Pete's friend is held. MacGyver breaks him out and hides him with the other patients