Two doctors fight over wether they should remove the leg of a diabetic patient.

Letty and Matt work together on a patient, Dean Carvell, who suffers severe heart problems due to a previous car accident. Dean's lover and son clash over his treatment, which doesn't seem successful. Finally, Dean must choose whether or not to continue being resuscitated. Meanwhile, Harriet unites a wealthy, infertile 42-year-old woman who desperately wants a child with a troubled, pregnant teenager, Ellen O'Neal, who wants to give up her baby for adoption. But problems with Ellen's father and teenage boyfriend could jeopardize the transaction. After suspecting parental abuse when she sees a boy's bruises, Jules later questions her decision to call Children's Protective Services. And each of the Presidio Med doctors passes an obnoxious chronic patient, Francis Weinod, on to the next unwitting physician.

Dr.Kokoris operates on another patient; A fitness instructor complains of muscle problems and learns he has something different.

Rae splits up from her husband Sean while helping a 9-year battle Leukemia.