The Main Pups try to get Cruella to quit her smoking habit when she has to move in with the Dearlys.

Cadpig liberates a lobster named Lance from his restaurant fish tank and tries to find a new home for him.

Lucky and Rolly compete on the game show Squeal of Fortune to win a bone autographed by Thunderbolt. Meanwhile, Cruella enters Scorch and Vendella into the show as well to advertise her new fashion pet wear. Then, Steven the alligator arrives and causes havoc at the show's end.

A Thunderbolt executive orders the Dearly Farm be used for the next episode of Thunderbolt. Lucky is overjoyed at the news. Despite this, when Lucky learns Thunderbolt doesn't do all his own stunts, which causes him to lose faith in his hero. Meanwhile, Cruella attempts to play a part in the production.

Spot runs away when she can't fit in with the pups or her family.

The pups tell of how the show 101 Dalmatians begin.

The pups try their best to help Roger find Anita, who is held captive by alien cultists who refuse to let her leave until their Shaggy-Green Messenger comes for them.