Prejudices come to the fore when the staff of Ward 17 discover they will be looking after a smuggler who is to be admitted with a bellyful of cocaine-filled condoms. The 'bloke' turns out to be a slip of a girl, who was once a junkie. The tragedy of her tale unfolds as she is monitored and guarded; she is desperately in love with her new husband, who is the only good thing to ever happen to her, and she wanted to help him realise his dream of a place in the country by smuggling coke — just this once. Her husband, Paul, has no intention of letting his wife go to jail, and puts a gun to Steph's head, he's getting his wife out of here! But Lisa needs surgery urgently. Paul will not let his wife out of his sight and when Luke points out that is not possible, Paul, at gunpoint, insists it is and that Luke must perform the surgery. Steph is roped in, and, Mitch volunteers himself as anaesthetist, rather then putting some other sucker at risk. The team heads off to surgery leaving Terri almost paralysed with fear. The last time there was a gun on the ward, two people died, and she eventually lost a man she cared deeply about. Von is the only one who realises what she is going through, and helps Terri cope as the ward is besieged with patients from the wing the theatre is in, evacuations having been necessary in case the gun goes off, exploding oxygen tanks.

In theatre, surgery goes ahead at gunpoint; Luke and Steph working on the patient as Mitch works hard to win Paul's trust and hopefully to get him to put away the gun. Just as it looks as if he has made a breakthrough, Luke nicks one of the condoms causing the cocaine to leak out and arrests lisa. The teams work to avert the crisis and once it seems clear Lisa will be all right, Paul insists they hand over the cocaine. There is shock for a moment as Mitch, Steph and Luke think this 'act of love' has in fact been about retrieving the drugs; but Paul slashes the condoms, tipping out the poison that has ruined his and Lisa's lives. He says a tearful goodbye to Lisa, hands Mitch the gun and walks out to face his fate. Leaving the surgical team to finish with Lisa and return to the arms of their waiting partners. As Steph and Ben embrace and Luke and Bron do likewise, Terri gives Mitch a stern lecture about the stupidity of putting his life at risk. Then Rose arrives and whisks Mitch away, leaving Terri alone.

Bron and Ben are called to an emergency in a local park, which turns out to be a pair of very embarrassed teenage sweethearts. Emily has called for help because Tim's penis is caught in his fly. Ben finally manages to release it and the young lovers head off hand in hand. The situation leads to Bron discovering more about the depth of Ben and Steph's feelings for each other.

The ward is abuzz with the news a female boxer is on the ward, suffering from concussion due to a knockout punch in training. Charlie and her trainer Jimmy are itching to get out of All Saints and back in the ring — she is not too keen on hanging around for a CT scan — even though Luke fears she may have a cerebral bleed. But Steph suspects there may be other factors behind Charlie's symptoms, and a urine test confirms she is pregnant. Terrified a pregnancy will mean the end of her boxing career, Charlie demands an abortion. There's only one hitch, Luke refuses to write a referral, claiming there is no medical reason for a termination.

While nursing Charlie, Steph realises the young boxers's views on pregnancy are not as clear cut as she initially made out — especially when Steph points out motherhood need not mean the end of her promising career. But even if Charlie is cleared of brain injuries, she still faces a terrible decision: abort the pregnancy or lose her big chance to crack the US professional circuit.

The best-laid plans of Terri and Regina start crumbling when an elderly patient dies only hours before her long-lost son arrives on a mercy dash from the UK. Flu-ridden Bryce Jones is devastated to discover his mother has just died, but a bigger shock awaits him when he views the body — it is not his mother. In his already weakened physical state the emotional upheaval is too much for Bryce, and he is admitted to Ward 17 suffering from pneumonia. When his condition worsens and Mitch eventually diagnoses advanced cancer, Regina decides it is time to bring some happiness into the unlucky man's life.

Ben faces a reunion of a different sort when his ambulance is hijacked by Jason Richards — a mixed up young man whose obsession with becoming an ambulance officer has developed into full-blown psychosis. Ben is stuck in the back of the ambulance with a critically ill patient, and needs all his wits to convince Jason to drive them to hospital before the patient dies. It is a race against time which Ben appears to be losing when the patient suffers a cardiac arrest. Ben knows the only way he can save the patient is by relying on Jason's assistance — but is it a risk he is prepared to take?

Connor and Bron are shocked to discover Jared has not yet had sex with his girlfriend Mel. Connor makes it his mission to get Jared laid, whether he wants it now or not.

Meanwhile, Steph's experiences with Charlie have forced her to re-evaluate her attitude to motherhood. It is the end of a long journey for Steph and she knows Ben will be overjoyed to hear she wants to start a family after all. What she did not bargain on is Ben dropping the biggest bombshell of their marriage.