Connor reckons Jared should stop sitting at home pining for Samantha and get out more. To this end, he hassles Jared into going to the gym with him. Jared is driving them both to the gym when he knocks over Roger, a very fit guy who trains for triathlons. Roger, who is a very full-on personality, leaps up and says he is fine. Jared wants the guy to have a check-up but Roger says he does not have time and cycles off. Jared sees Roger again at the gym and is amazed by his fanatical approach to training. At the gym, Jared also meets Mel, an attractive instructor. As Jared leaves for work he finds Roger collapsed on the side of the road. Jared calls the ambulance. At the hospital it takes a while for Mitch to diagnose Roger, who is going into body meltdown (Rhabdomyolysis). Roger admits to Mitch he has used training as a way to avoid confronting his feelings about a broken relationship. This admission and a subsequent conversation with Mitch propels Jared back to the gym to ask Mel out on a date.

Connor is delighted to find Cougars star Darren Rigg admitted to Ward 17 and under his care. Darren is a fervent and very public anti-drugs campaigner. He is faced with the treatment decision of whether or not to use a steroid medication to make the football injury heal faster. If he does not take the steroids, he will not heal in time to take the field for the Grand Final. But, if he does take them, he feels it could compromise his anti-drugs position. Darren's fiancee is none other than Simone Carlisle. She is a drug addict who has managed to clean herself up but has hepatitis C. She agrees to allow Mitch to perform a liver biopsy but does not want to tell Darren about her hep C or her past. Simone's presence in the hospital is the talk of the ward, particularly as she may have inadvertently passed the hep C on to Tony via his needlestick injury.

Luke falls into the trap of joining in laughter at Steph's expense over the incident (in the previous episode) where she was responsible for a patient losing confidence in a doctor. This week, however, it is Luke's turn. Olivia, a large diabetic woman, has a reaction to antibiotics and can't breathe. Luke mucks up his attempt to intubate her. Swelling around her throat forces him to do a tracheostomy. After he cuts her neck open, he cannot find the windpipe in all the blood and gore. Stan Ridgeway, who is on the ward looking for Steph's incident report, come to Luke's rescue and the patient is saved. But Luke is completely humiliated.

Terri is forced to come to work out of uniform because both her uniforms were stolen from the clothesline, along with some of her underwear. The main suspect is Neil Phillips.

Ben and Steph's romance heats up, with Ben sending flowers to the ward and Steph slipping a note under a windscreen wiper on the ambulance. The flowers are a source of confusion to Terri, who thinks they are from Luke as a means of apologising to Steph.