In the middle of the battle against the demons on the artificial island, Kisara was stabbed by a spear before Shu's eyes. Saved by Ayano and Sharon, Shu helplessly evacuates from the fight when he sees the person he's been looking for—his younger sister, Kanna. Then, humanity's desperate resistance, backed by the focused efforts of Bayron City, proves futile as the extent of the large-scale disasters caused by Kanna, now certified as an S-Class demon, expand. Kisara collapsed due to her injuries and lost consciousness as her vitals disappeared. Unable to move, Shu just stares at her. And as if responding to his heart, Kisara gently awakens.

Shu is always in trouble with money but manages to live thanks to the support given by his ex-girlfriend Ayano and the ever-devoted Kisara. The same goes for his job as a PMC. With Ayano's cooperation, Shu won a bidding war at a discounted price to participate in the "D Hazard" prevention operation that occurred in a casino. At the scene of the demon extermination, he planned to rely on Kisara's demonic powers, but she is nowhere to be found due to the money situation ruining her mood. As a last resort, he works with Ayano's leading, major PMC and confronts the Demon, but bit by bit, the battle becomes something suspicious...

In the chaotic mix of humans and demons, Shu and Kanna meet in a violent clash worthy of their 12-year-gap as various motives intermingle in a battle engulfed by a sea of flames. Ayano, Sharon and Kisara try to somehow intervene in the siblings' fight that puts the fate of the world at stake. The only way to stop a powerful demon is with the power of a demon. Shu and Kisara join hands once again. Will the accumulation of their feelings reach Kanna, embroiled in her rage? At the end of the battle, what future lies ahead for humans and demons alike?