With Leonard away, Sheldon and Penny spend quality time together sharing intimate secrets. Also, Wolowitz helps Raj get over his ex-girlfriend.

Leonard and Sheldon's friendship is tested; Howard's latest foray into helping his mother has some disastrous side effects.

When the entire gang competes in a scavenger hunt designed by Raj, it brings out the best - and worst - in everyone.

Sheldon gets mad at Amy for ruining one of his favorite movies, Raj and Stuart try to make their online dating profiles more appealing, and Leonard tries to play the sympathy card with Penny.

Amy starts working at Caltech which causes friction with Sheldon. Howard agrees with Sheldon who mentions this to Bernadette causing a big fight for the Wolowitzes.

Sheldon's latest scientific breakthrough leaves him feeling like a fraud; a romantic gesture between Howard and Bernadette causes Penny to up her game with Leonard.

Sheldon seeks payback when Arthur "Professor Proton" Jeffries asks Leonard for help on a project instead of him. Raj gets upset at Howard for crashing his night with the girls.

When a mistake comes to light, Sheldon makes Leonard walk a mile in his shoes; Penny decides to confront Raj's ex-girlfriend, Lucy.

Sheldon protests when the gang drags him to Mrs. Wolowitz’s house for Thanksgiving. Meanwhile, Penny and Leonard must deal with a mistake from her past.

Leonard has to deal with the fallout of disproving Sheldon's new scientific discovery. Raj spends a week at Howard and Bernadette's apartment.

While Sheldon is at home in Texas, the rest of the gang realizes how much he has changed their lives as they decorate the apartment Christmas tree.

When Penny’s big acting break on NCIS is a bust, Leonard struggles to help her, which results in Penny asking Leonard a bold relationship question. Meanwhile, Raj and Stuart try to practice their social skills, and Sheldon navigates the intricacies of being funny.

Sheldon tries to relax after he is forced to take a vacation. Meanwhile, Leonard struggles to be supportive of Penny after she quits her job, and Bernadette seeks Stuart’s help in replacing one of Howard’s comic books. Also, Amy receives an unwanted attention from a co-worker.

After the guys can’t get Comic-Con tickets, Sheldon tries to hold his own convention and winds up spending a wild night with James Earl Jones. Meanwhile, the girls try to feel more mature by going to a fancy hotel for tea.

Sheldon and Amy take a train ride to Napa Valley with Howard and Bernadette on Valentine's Day. Leonard and Penny take Raj's dog to the vet when she accidentally eats some chocolate.

Leonard buys a dining room table and it causes Sheldon to reevaluate the changes in his life. Meanwhile, Wolowitz is offered a chance to go back to space and Bernadette struggles with whether or not to encourage him.

After arguing with Sheldon, Howard tries to make amends by taking him to NASA headquarters in Houston. Penny has second thoughts about quitting her waitressing job when her car dies. Amy gets involved in trying to find Raj a date.

When Sheldon visits his Mom in Houston, he is forced to confront a new reality. Meanwhile, Raj’s ‘Murder Mystery’ party starts some fights within the gang.

While Raj is wracked with guilt when he tries to date two women at once, Penny wrestles with whether to take a role in a cheesy movie and Sheldon is torn trying to choose between two gaming systems.

Sheldon faces a personal crisis after deciding he’s wasting his time with string theory. Meanwhile, a double date between Raj, Emily and the Wolowitzes ends in embarrassment for Howard.

To prepare for a date with Emily, Howard acclimates Raj to horror movies. Penny and Sheldon are upset when they discover Amy and Bernadette lied to avoid hanging out with them.

As the gang celebrates Star Wars Day, Sheldon has difficulty dealing with the recent death of Arthur "Professor Proton" Jeffries.

A bad day causes Penny to reevaluate her life choices – including Leonard. Meanwhile, Howard and Bernadette struggle to care for Mrs. Wolowitz, and Raj gets relationship advice from Sheldon.

Sheldon get upset about his career, the destruction of the comic book store and Leonard and Penny's future living arrangements. Howard and Bernadette can't keep hold of a caretaker for his mother. With his entire world changing around him, Sheldon considers a major move.

Leonard and Amy make an unexpected trip to Arizona to fetch Sheldon; Penny interviews for a job at Bernadette's company; Stuart's relationship with Mrs. Wolowitz disturbs Howard.

Sheldon is forced to teach a class as a Junior Professor and Howard decides to enroll in it. Meanwhile, Amy plays both sides when tension arises between Penny and Bernadette.

Wolowitz feels nervous when he is asked to throw the first pitch at a Los Angeles Angels game. Penny and Leonard want to prove Sheldon wrong after he says he and Amy are the better couple.

Raj's honesty comes back to haunt him when his new girlfriend is unfriendly to Penny. The guys think about becoming part owners in Stuart's store.

The girls head to Las Vegas for some weekend fun, while the guys try to invent something cool, but only come up with new ways to procrastinate.

Sheldon and Raj test whether they could survive a dark-matter research expedition in a salt mine by simulating the conditions in a steam tunnel deep underground. Meanwhile, Leonard and Penny seek advice from Howard and Bernadette after they fight about money.

The guys try to help Penny out of an awkward work dilemma, when a smitten doctor shows up at her door after her flirtatious sales techniques work a little too well. Meanwhile, Amy and Bernadette argue over whether or not female scientists should play up their sexuality.

The girls decide to re-enact their high school proms with the guys. While Sheldon feels under pressure to commit to his relationship with Amy, Howard worries about who Stuart will bring as his date.

When Leonard gets minor surgery on his nose, Sheldon is the one in need of sympathy. Meanwhile, Raj's parents' impending divorce causes Howard and Bernadette to work on their own marriage.

While Sheldon says a tearful goodbye to the final installment of "Fun with Flags", Leonard, Howard and Raj search for something significant in a dead professor's research. And Bernadette finds out what her colleagues really think of her.

Leonard and Howard turn to Raj for help in dealing with a work emergency when they nearly come to blows after blaming each other for a potential disaster at the university. Amy throws an authentic Victorian Christmas party, while Sheldon seeks revenge on her for making him celebrate the holidays.

Howard tries to distract Raj, who is anxiously awaiting data from a space probe he helped launch. Meanwhile, Sheldon and Leonard go dress shopping with Penny and Amy.

When Sheldon becomes stuck in a rut with his work, the gang tries to help him by raising his stress levels. Howard teases Raj with a game called "Emily or Cinnamon?"

Leonard and Sheldon publish a paper which is widely accepted except for comments from an internet troll. Meanwhile, the girls reminisce about embarrassing incidents from their past.

Howard receives some shocking news as everyone prepares for the reopening of Stuart’s comic book store. Penny teaches Sheldon how to “let it go,” but can’t follow her own advice after she learns something infuriating about Amy. Also, Leonard and Raj think they spot Nathan Fillion at a restaurant.

As a joke, Sheldon and Penny try an experiment designed to make participants fall in love. Meanwhile, Leonard, Amy, Raj and Emily spend the evening trying to escape a room with a “zombie.” And, after returning from Mrs. Wolowitz’ funeral, Bernadette and Howard run into trouble at the airport.

A trip to the pet store ends in a fight after Amy learns Sheldon has applied for a one-way mission to colonize Mars. Meanwhile, Leonard surprises Penny with a very "adult" purchase, and Raj gets into trouble when he snoops around Emily's apartment.

Friction ensues when a magazine fails to mention Leonard in an article about the paper he co-wrote with Sheldon. Also, a blackout at Mrs. Wolowitz’s home leads to a final family dinner in her honor.

When Leonard and Sheldon are invited to speak at UC Berkeley, they take a detour to try to meet an idol. Also, when Bernadette and Howard battle over the fate of his Doctor Who TARDIS, Raj and Amy offer to settle the dispute with a game of ping pong.

When Sheldon and Amy build a blanket fort, they come to major crossroads in their relationship. Also, Howard meets the half-brother he never knew he had. Meanwhile, Penny is invited to appear on Wil Wheaton’s podcast, but things turn awkward when Leonard joins them.

When Raj is asked to create a message in case a NASA mission discovers alien life, the guys fight over what he should do. Also, Penny is torn between auditioning for a movie or keeping her successful pharmaceutical sales job.

Howard questions his engineering abilities when he and Sheldon can’t get a toy drone to fly. Meanwhile, a cancelled flight nearly prevents Leonard from giving the commencement address at his former high school, and Raj pits his parents against each other when his father cuts him off financially.

Personalities collide when Sheldon and Leonard’s mothers finally meet. Meanwhile, Howard finally decides to “man up” and do his fair share of the housework – but not without a little help from his friends.

As Sheldon presses Leonard and Penny to set a wedding date, he encounters major changes in his own relationship with Amy. Meanwhile, Raj contemplates breaking up with Emily, and Howard and Bernadette struggle with asking Stuart to move out of their house.

After driving to Vegas to get married, Penny struggles with Leonard’s confession that he kissed another girl. Also, Sheldon doesn't know how to act after Amy pushes pause on their relationship.

Leonard confronts the woman he kissed on the North Sea in an attempt to set Penny's mind at ease. Also, Sheldon films a special episode of "Fun with Flags" after his breakup with Amy, and Bernadette feels guilty about withholding a secret from Penny.

The guys' science skills are put to the test when they get a flat tire during Leonard's bachelor party weekend in Mexico. Also, the girls force Penny to finally tell her family that she eloped with Leonard.

Sheldon learns of an impending change in his living arrangements and decides to revert back to 2003, a simpler time before he met Leonard and Penny. Also, Howard and Raj form a band to play at the Comic Book Store.

The guys take a fencing lesson from Barry Kripke and Sheldon finds himself in an awkward position when Kripke expresses interest in Amy. Also, when Stuart struggles to get female customers at the Comic Book Store, Penny, Amy and Bernadette come by to help him out.

In the midst of a nation-wide helium shortage, Sheldon and Leonard take desperate measures to get the supplies they need. Also, Penny and Bernadette download a dating app on Amy's phone to try and find her a new man.

Wil Wheaton interviews Sheldon for a Star Trek documentary where he reveals the ring and his plan to propose to Amy. Bernadette wants to start renovating the house and the topic of starting a family together with Howard is brought up.

Sheldon, Wolowitz and Koothrappali post an online advertisement to find Sheldon a new girlfriend. Also, when Amy is coy with details about a guy she is dating, Penny and Bernadette decide to spy on her.

Sheldon and Amy try hanging out as friends when they spend Thanksgiving together at the aquarium. Also, Wolowitz reluctantly agrees to volunteer at the soup kitchen with Bernadette, Raj and Emily, and Penny discovers that Leonard knows more about her than she thought.

Sheldon has a revelation when he realizes why a song was stuck in his head. Also, Amy invites Dave over for dinner despite their previously awkward date, and Wolowitz and Koothrappali become obsessed with a fan of their band, "Footprints on the Moon".

After more than five years of dating, Sheldon and Amy spend their first night together. Also, Leonard, Wolowitz, and Koothrappali must decide who will take their extra Star Wars movie ticket.

Penny gets more than she bargained for when Leonard agrees to meet with a psychiatrist on her behalf. Also, Sheldon and Koothrappali collaborate on an astronomical discovery, and Wolowitz and Bernadette can't believe what they are feeling after Stuart moves out.

After having to deal with a sick Sheldon, Leonard, Penny and the gang try to treat themselves to a Sheldon-free weekend.

Meemaw meets Amy, but it isn't all roses. Meemaw seems to have an axe to grind with her. Sheldon comes to Amy's defense, but not before Meemaw lets a little secret of his slip.

Sheldon and Amy host a live Valentine's Day episode of Fun with Flags, Leonard and Penny grapple with getting older, Howard and Bernadette find a surprise in their hot tub and Raj is torn between Emily and the cute girl he met at the Comic Bookstore.

When the gang finds out about Bernadette’s pregnancy, they celebrate by singing karaoke. Also, Bernadette is concerned when Wolowitz freaks out over her pregnancy announcement, and Wolowitz is convinced he must make more money to provide for the baby.

After more than nine years together, the gang finally celebrates Sheldon’s birthday, surprising him with a special guest.

Leonard, Sheldon, and Wolowitz run into problems when they file for a patent for their infinite persistence gyroscope. Also, Penny, Amy and Bernadette give Koothrappali dating advice when Emily reaches out to him after their breakup.

Amy is shocked at a revelation from Sheldon after she buys him a new laptop. Also, Koothrappali sells out Leonard and Wolowitz after they lie to their wives in order to attend an early screening of a movie.

Sheldon spills a secret of Leonard’s when the two take a weekend cabin trip with Penny and Amy. Also, when Koothrappali goes overboard with pregnancy gifts, Wolowitz and Bernadette must draw the line.

Everyone must choose sides when a small argument between Leonard and Sheldon erupts into a heated fight during a group get-together.

The gang goes to a wine bar and runs into Penny’s old boyfriend, Zack. Also, Bernadette gets stuck spending the evening with Sheldon when she can’t go wine tasting with the group, and things don’t go as planned when Koothrappali introduces his new girlfriend, Claire.

Sheldon hires Stuart to spend the day with Amy when he’d rather go to a movie screening. Also, Leonard’s mother, Beverly, comes to town and Penny struggles to make a connection with her.

Chaos ensues when Leonard’s recently divorced parents, Alfred and Beverly, and Sheldon’s devoutly religious mother, Mary, come to town. Also, Wolowitz and Koothrappali think the government is out to get them when they are contacted about their guidance system.

After Sheldon’s mother and Leonard's father share an evening together, everyone deals with an awkward morning the next day. Also, Penny’s family arrives for the wedding ceremony, including her anxiety-ridden mother, Susan, and her drug dealing brother, Randall.

Colonel Williams, an Air Force representative from the Department of Material Command sits down to talk with Wolowitz.

Tensions rise when the boys struggle to complete their government project on time and Sheldon tries an energy drink to stay awake. Also, Penny and Amy go to a “party” at Bert the geologist’s house, and Koothrappali learns Bernadette’s true feelings about her pregnancy when they clean out the future baby room.

When Amy’s apartment floods, she proposes a “cohabitation experiment” with Sheldon. Also, Howard and Bernadette are upset when Koothrappali learns the gender of the baby before they do.

Leonard and Penny must separate a quarreling Sheldon and Amy when their cohabitation does not go as planned, and Sheldon threatens to break off their relationship when Amy refuses to adhere to the bathroom schedule. Also, Howard and Bernadette find unexpected guests at their house when they decide to stay home from a planned vacation.

Penny is surprised to learn she has fans of her performance in "Serial Ape-ist" when she attends Van Nuys Comic Con with Leonard. Also, Amy hosts a Sheldon-style brunch at Penny’s apartment, and Wolowitz makes an impulsive purchase when he starts stressing out about the baby on the way.

In order to continue living with Sheldon, Amy lies to him about repairs being made to her apartment and they host an "on location" episode of "Fun With Flags" in Penny’s apartment. Also, Leonard lets Penny decorate Sheldon’s old room after he learns that she has been secretly moving Leonard’s collectibles into storage.

After a successful experiment combining their genes, Sheldon will stop at nothing to convince Amy they should procreate. Also, Koothrappali is embarrassed to tell the gang what the new woman he’s dating does for a living.

When Bert, a Caltech geologist, wins the MacArthur Genius fellowship, Sheldon is overcome with jealousy. Also, Wolowitz finds an old remote control Stephen Hawking action figure he invented.

Sheldon and Leonard try to divvy up their shared belongings, but can’t agree on anything. Also, Koothrappali and Stuart fight to be the most helpful during Bernadette’s final weeks of pregnancy.

Howard and Bernadette welcome their new baby and Sheldon and Amy celebrate Amy’s birthday.

Sheldon and Amy visit Leonard and Penny for the first time since the holidays and share details about their terrible trip to Texas.

When Penny feels that Leonard is taking her for granted, she decides to go on a spa weekend with Amy. Also, Wolowitz and Koothrappali try to fix a squeaky floorboard in the baby’s room.

Sheldon beta-tests an MIT invention after hearing it can help him read people’s emotions. Also, Leonard can’t hide his feelings when Penny announces her brother is coming to town, and Raj invites his ex-girlfriends over to give him dating advice.

Leonard and Wolowitz try to distract Sheldon when he slows the progress of their guidance system. Also, Penny and Amy take Bernadette out for the night, leaving Raj and Stuart to care for baby Halley.

Sheldon and Amy have their first fight since moving in together, and Koothrappali is shocked at the realities of financial independence when he stops receiving support from his father.

With Koothrappali cut off from his father’s fortune, he appoints Sheldon to help him get out of debt. Also, Penny considers joining Leonard at Comic-Con.

When Raj moves out of his apartment, Leonard and Penny offer him Sheldon's old room.

Leonard, Penny and Raj adjust to their new living arrangement, and Sheldon takes an interest in Amy’s work.

Sheldon pushes himself to the limit when he collaborates on projects with Leonard and Wolowitz as well as Amy on the same day. Also, Bernadette is nearing the end of her maternity leave and must return to work.

Howard and Bernadette have a hard time leaving Halley in day care when Bernadette returns to work. Also, Bert introduces the gang to his new girlfriend, Rebecca.

Leonard isn’t thrilled when Penny considers taking a new job offered by her ex-boyfriend, Zack.

After Leonard, Sheldon and Wolowitz celebrate the completion of the top secret air force project, they are met with an unpleasant surprise. Also, Amy is offered a summer position as a visiting researcher.

The gang is concerned when Sheldon’s former admirer, Dr. Ramona Nowitzki, resurfaces while Amy is away at Princeton.

In the eleventh season opener, Amy gives Sheldon an answer to his proposal while Howard and Bernadette struggle with some unexpected news.

Leonard angers the university – and the entire physics community – after he gives an embarrassing interview. Also, Amy and Bernadette bond over having to hide their success from Sheldon and Howard.

Sheldon and Amy struggle with picking a wedding date, which stresses out Sheldon and causes him talking in his sleep. Meanwhile, Raj and Stuart fight over the attention of one of Bernadette's co-workers.

As Howard worries about fatherhood, he and Sheldon bond when they jointly assemble a model rocket. Meanwhile, Penny bonds with Leonard's mother, Beverly, much to his concern.

Sheldon and Raj confide in Bernadette when they can't handle Amy and Howard working together on a science project. Also, Penny and Leonard learn new tactics for how to deal with Sheldon from an unlikely source.

Sheldon goes head-to-head with Wil Wheaton for the role of the new Professor Proton. Also, Penny steps in to take care of Halley when Bernadette and Howard both wind up on bed rest.

Sheldon and Bert collaborate on a research project, despite Sheldon’s embarrassment. Also, Penny and Bernadette coach Raj on how to navigate his relationship with Ruchi.

Leonard and Howard are furious after they learn Sheldon went to work with the military behind their backs. Also, while Bernadette is on bed rest, she asks Raj to do some digging when she suspects that Ruchi might be trying to take over her projects at work.

Sheldon tries to teach the guys a lesson after they cut him out of a potentially valuable Bitcoin investment. Also, a seven-year-old video reveals a secret about Leonard and Penny's relationship.

Sheldon and Amy try to eliminate stress from wedding planning by applying math to the process. Also, Raj “breaks up” with Howard after realizing his best friend is actually hurting his confidence.

Raj and Howard's feud continues as the gang plan Halley's first birthday party. Sheldon's surprise for Amy's birthday goes awry when they get food poisoning. Also, Leonard gets a Christmas letter from his brother that causes him to spiral out about his own lack of accomplishments.

Sheldon and Amy try to pick their Best-Man and Maid of Honor by experimenting on the gang.

When Sheldon kicks Amy out to work solo, she and Leonard bond during a series of science experiments. Also, Bert the geologist replaces Wolowitz in the band Footprints on the Moon, and Sheldon finds Penny a surprising source of scientific inspiration.

Raj finds himself in the middle of domestic drama when he learns the woman he's dating, has a very upset husband. Also, when Sheldon rents his old room back for a quiet place to work, he drives Leonard crazy by being a model tenant.

Leonard's book raises questions, and Amy guest stars on the new Professor Proton show.

When Bernadette won't go into labor, the gang tries different tactics to get things started. Also, Howard confronts Bernadette after Amy accidentally reveals she's already chosen their son's name.

Leonard jumps through hoops to help secure the perfect wedding venue for Sheldon and Amy. Also, Bernadette and Howard have a hard time deciding who should stay at home with the kids and who should go back to work.

Bill Gates visits Penny's work, and the gang schemes to meet him. Hilarity ensues. Meanwhile, Sheldon is convinced that he's a target of an April's Fools prank.

When Leonard learns Sheldon is the president of the tenants association, he decides to run against him. Also, Bernadette encourages Howard and Raj to find the owner of a drone after they find it in the backyard.

A brilliant but reclusive scientist, Doctor Wolcott, invites Sheldon to his cabin in the middle of nowhere, and Leonard, Raj and Howard go along for the trip. Also, Penny and Bernadette improvise after Amy doesn’t like the tame bachelorette party they planned for her.

Sheldon’s comic book store experiences changes when writer Neil Gaiman puts Stuart’s store on the map. Also, friendships are threatened when Raj takes credit for Penny's astronomical discovery.

Sheldon goes to Vegas to win money for science. Also, Penny and Bernadette take Amy wedding dress shopping, but her terrible choice entangles them in a web of lies.

When Sheldon learns that his mother won’t attend his wedding unless he invites his brother, Georgie, he and Leonard travel to Texas to end a family feud. Also, the Wolowitz kids inadvertently infest Amy, Bernadette, Howard and Raj with pinkeye.

When Amy's parents and Sheldon's family arrive, everybody is focused to make sure all wedding arrangements go according to plan – everyone except the bride and groom.

Sheldon and Amy's honeymoon runs aground in New York. Penny and Leonard discover they are uncomfortably similar to Amy's parents. Raj insults physicist Neil deGrasse Tyson and starts a Twitter war.

Sheldon and Amy drive themselves crazy trying to figure out what 'perfect gift' Leonard and Penny gave them for their wedding. Raj decides he wants to settle down and asks his father to arrange a marriage for him.

The Wolowitzes' life gets complicated when Stuart starts bringing his new girlfriend home. Also, Penny and Leonard talk about starting a family, while Raj explores an arranged marriage.

When Sheldon won't tell anyone why he's never mentioned his childhood best friend, Leonard takes matters into his own hands. Bernadette and Penny take out Raj’s fiancée for dinner to get the skinny on her.

When Amy doesn’t have time to work on super-asymmetry, Sheldon goes to great lengths to ensure she’s available to work with him even it if means accidentally sabotaging her career in the process. Raj doesn’t want Howard to join him in hosting a show at the planetarium.

When Howard dresses up as Sheldon for Halloween, Sheldon seeks retaliation at Leonard and Penny's Halloween party. Leonard is shocked that Penny doesn't remember their first kiss.

Leonard is caught between a rock and a hard place when he's responsible for distributing extra grant money. Bernadette turns the backyard playhouse into a hideaway from Howard and the kids.

Sheldon tries to bond with Amy's father, but when Howard lures Mr. Fowler away with magic tricks, Sheldon has no choice but to bond with Mrs. Fowler. Raj and Anu try to get physical for the first time.

Sheldon and Amy are devastated after learning from a Russian paper that Super Asymmetry has already been theorized and disproven. Meanwhile, ultra-competitive Bernadette asks Stuart’s girlfriend to teach her how to beat Howard in a popular video game.

Sheldon and Amy are still down about their theory being disproven, but a VHS tape from Sheldon’s past inspires him not to give up. Bernadette turns into a pageant mom when she tries to help Howard ace his Magic Castle audition.

Penny and Leonard organize a paintball game that results in mayhem when Sheldon is jealous of Amy. Also, Raj catches Anu with her ex-boyfriend, and Stuart gets cold feet when Denise hints at the possibility of them living together.

Penny runs into her ex-boyfriend, Zack, who invites her and Leonard to a dinner to meet his newlywed wife. After the dinner the newlywed couple make an odd proposition to Leonard, which makes Penny to freak out. Also, Raj attempts to mend things with his ex-fiancée, Anu.

Sheldon and Amy are thrilled when their super asymmetry theory is proven by two physicists, until they try to kick Amy off the Nobel nomination. Also, Bernadette gets one of her drugs approved at work and wants a reluctant Penny to head the sales team.

Sheldon is thrilled to help Bernadette and Wolowitz navigate bureaucratic paperwork, until he discovers they are breaking the law. Also, Leonard is disappointed when his friends exclude him from a scientific project.

Penny tries to seduce an abstaining Leonard to ruin his "donation" for her ex-boyfriend, Zack, and his wife, Marissa. Also, Wolowitz, Bernadette, Anu and Koothrappali turn Koothrappali's canceled bachelor party into a couple's trip.

The gang finds out Wil Wheaton hosts a celebrity Dungeons and Dragons game involving William Shatner, Joe Manganiello, Kareem Abdul-Jabbar and Kevin Smith. Deception and betrayal are the path to make it to the one open seat.

When Penny and Bernadette go to San Diego for a pharmaceutical sales convention, Wolowitz is in charge of the kids. Also, Sheldon finds a book on experimenting on kids, and the guys plus Amy make a day of it.

When competitors Pemberton and Campbell charm America on a publicity tour, Sheldon and Amy try to bring Nobel laureates Kip Thorne, George Smoot and Frances Arnold to their side. Also, Halley's fear of the dark causes opportunity and conflict at the Wolowitz home.

The concept of what it would mean for women everywhere if Amy were to win a Nobel Prize causes Amy to have a meltdown. Also, Howard and Raj try to relive the good old days after Howard buys a scooter that looks like the one he had years ago.

Raj is worried people won’t take him seriously in his own field after publishing a paper that suggests he may have discovered alien life. Also, Leonard wants to be the principal investigator on a plasma physics study.

Kripke has proof that Dr. Pemberton plagiarized his thesis in college, and Sheldon and Amy aren't sure if they should turn him in or not. Meanwhile, Howard learns that Bernadette wasn't the only waitress at the Cheesecake Factory who had a crush on him.

Leonard is pleasantly surprised when Beverly comes to visit and she's genuinely kind to him, until he finds out the real reason she's there. Also, Denise and Stuart overstay their welcome at the Wolowitz house.

Sheldon and Amy await big news. Meanwhile, Penny and Leonard have some big news of their own. Also, Howard and Bernadette face the stressful challenge of leaving their kids for the first time and Raj makes a new friend, as the gang travels together into an uncharted future.

Johnny Galecki and Kaley Cuoco will lead fans on a trip down memory lane, sharing some of the best-kept backstage secrets and personal memories from the past 12 years.