The series begins in the summer of 2019 and follows 43 year-old Chris, as he awaits news of his daughter's blood test results for the same gene and faces a big test himself: his driving assessment. Gilly, 74, and his wife Christine are trying to make the best of their retirement, spending time with their friends at their holiday home in Spain and with their grandchildren back in Bradford.

This episode looks at the effects on those with dementia as the pandemic hits and Britain goes into lockdown. As social interaction helps keep the brain active, it proves to be a very difficult time.